Growing in Antarctica, a challenge for white adipose tissue development in Adélie penguin chicks (Pygoscelis adeliae)
Entry ID: 131_9_IPEV_FR

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Summary
Abstract: Rapid growth is of crucial importance for Adélie penguin chicks reared during the short Antarctic summer. It partly depends on the rapid ontogenesis of fat stores that are virtually null at hatching but then develop considerably (40) within a month to constitute both an insulative layer against cold and an energy store to fuel thermogenic and growth processes. The present study was aimed at identifying by
RT-PCR the major transcriptional events that chronologically underlie the morphological transformation of adipocyte precursors into mature adipocytes from hatching to 30 days of age. The peak expression of GATA binding protein 3, a marker of preadipocytes, at day 7 posthatch indicates a key proliferation step, possibly in relation to the expression of C/EBPalpha (C/EBPalpha). High plasma total 3,5,3'-triiodo-Lthyronine (T3) levels and high levels of growth hormone receptor transcripts at hatching suggested that growth hormone and T3 play early activating roles to favor proliferation of preadipocyte precursors. Differentiation and growth of preadipocytes may occur around day 15 in connection with increased abundance of transcripts encoding IGF-1, proliferator-activated receptor-gamma, and C/EBPbeta, gradually leading to functional maturation of metabolic features of adipocytes including lipid uptake and storage (lipoprotein lipase, fatty-acid synthase) and late endocrine functions (adiponectin) by day 30. Present results show a close correlation between adipose tissue development and chick biology and a difference in the scheduled expression of regulatory factors controlling adipogenesis compared with in vitro studies using cell lines emphasizing the importance of in vivo approaches.

Data Set Citation
Dataset Originator/Creator: Mireille Raccurt, Fannie Baudimont, Julien Tirard, Benjamin Rey, Elodie Moureaux, Alain Géloën and Claude Duchamp
Dataset Title: Growing in Antarctica, a challenge for white adipose tissue development in Adélie penguin chicks (Pygoscelis adeliae)
Dataset Release Date: 0000-00-00
Issue Identification: Am J Physiol Regul Integr Comp Physiol 295: R1671–R1679, 2008


Location Keywords
CONTINENT > ANTARCTICA > Adélie
CONTINENT > ANTARCTICA > Terre
CONTINENT > ANTARCTICA
GEOGRAPHIC REGION > POLAR


Science Keywords
AGRICULTURE >ANIMAL SCIENCE >ANIMAL PHYSIOLOGY AND BIOCHEMISTRY    [Definition]
BIOLOGICAL CLASSIFICATION >ANIMALS/VERTEBRATES >BIRDS >PENGUINS
BIOSPHERE >ECOLOGICAL DYNAMICS >SPECIES/POPULATION INTERACTIONS >EVOLUTIONARY ADAPTATION    [Definition]


ISO Topic Category
BIOTA
ENVIRONMENT


Keywords
Adelie penguin
white adipose tissue
adipogenesis
growth
adipocyte
gene expression
thermoregulation
cold adaptation
energy storage
energy balance


Data Center
Laboratoire de Physiologie Intégrative, Cellulaire et Moléculaire
Data Center URL: http://ufr-biologie.univ-lyon1.fr

Data Center Personnel
Name: CLAUDE DUCHAMP
Phone: 0472448138
Email: claude.duchamp at univ-lyon1.fr
Contact Address:
43 bld 11 nov 1918
City: Villeurbanne
Postal Code: 69622
Country: France


Personnel
CLAUDE DUCHAMP
Role: DIF AUTHOR
Phone: 0472448138
Email: claude.duchamp at univ-lyon1.fr
Contact Address:
43 bld 11 nov 1918
City: Villeurbanne
Postal Code: 69622
Country: France


MIREILLE RACCURT
Role: INVESTIGATOR
Role: TECHNICAL CONTACT
Email: mireille.raccurt at univ-lyon1.fr
Contact Address:
43 bld 11 nov 1918
City: Villeurbanne
Postal Code: 69622
Country: France



Creation and Review Dates
DIF Creation Date: 2009-11-16
Last DIF Revision Date: 2012-01-25

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